We have located links that may give you full text access.
Journal Article
Review
Photobiomodulation: Implications for Anesthesia and Pain Relief.
Photomedicine and Laser Surgery 2016 December
OBJECTIVE: This review examines the evidence of neural inhibition as a mechanism underlying pain relief and anesthetic effect of photobiomodulation (PBM).
BACKGROUND: PBM for pain relief has also been used for more than 30 years; however, the mechanism of its effectiveness has not been well understood.
METHODS: We review electrophysiological studies in humans and animal models and cell culture studies to examine neural responses to PBM.
RESULTS: Evidence shows that PBM can inhibit nerve function in vivo, in situ, ex vivo, and in culture. Animal studies using noxious stimuli indicate nociceptor-specific inhibition with other studies providing direct evidence of local conduction block, leading to inhibited translation of pain centrally. Evidence of PBM-disrupted neuronal physiology affecting axonal flow, cytoskeleton organization, and decreased ATP is also presented. PBM changes are reversible with no side effects or nerve damage.
CONCLUSIONS: This review provides strong evidence in neuroscience identifying inhibition of neural function as a mechanism for the clinical application of PBM in pain and anesthesia.
BACKGROUND: PBM for pain relief has also been used for more than 30 years; however, the mechanism of its effectiveness has not been well understood.
METHODS: We review electrophysiological studies in humans and animal models and cell culture studies to examine neural responses to PBM.
RESULTS: Evidence shows that PBM can inhibit nerve function in vivo, in situ, ex vivo, and in culture. Animal studies using noxious stimuli indicate nociceptor-specific inhibition with other studies providing direct evidence of local conduction block, leading to inhibited translation of pain centrally. Evidence of PBM-disrupted neuronal physiology affecting axonal flow, cytoskeleton organization, and decreased ATP is also presented. PBM changes are reversible with no side effects or nerve damage.
CONCLUSIONS: This review provides strong evidence in neuroscience identifying inhibition of neural function as a mechanism for the clinical application of PBM in pain and anesthesia.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app