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Elevated GDF11 Is a Risk Factor for Age-Related Frailty and Disease in Humans.

David J Glass
Cell Metabolism 2016 July 13
GDF11 was reported to decline with age and to have muscle and heart rejuvenating effects. These reports were disputed. A Cell Metabolism paper now shows that in human beings, GDF11 does not decline with age and is actually a risk factor for frailty and other morbidities (Schafer et al., 2016).

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