Add like
Add dislike
Add to saved papers

Multi-Tissue Decomposition of Diffusion MRI Signals via Sparse-Group Estimation.

Sparse estimation techniques are widely utilized in diffusion magnetic resonance imaging (DMRI). In this paper, we present an algorithm for solving the ℓ0 sparse-group estimation problem and apply it to the tissue signal separation problem in DMRI. Our algorithm solves the ℓ0 problem directly, unlike existing approaches that often seek to solve its relaxed approximations. We include the mathematical proofs showing that the algorithm will converge to a solution satisfying the firstorder optimality condition within a finite number of iterations. We apply this algorithm to DMRI data to tease apart signal contributions from white matter, gray matter, and cerebrospinal fluid with the aim of improving the estimation of the fiber orientation distribution function (FODF). Unlike spherical deconvolution approaches that assume an invariant fiber response function (RF), our approach utilizes an RF group to span the signal subspace of each tissue type, allowing greater flexibility in accounting for possible variations of the RF throughout space and within each voxel. Our ℓ0 algorithm allows for the natural groupings of the RFs to be considered during signal decomposition. Experimental results confirm that our method yields estimates of FODFs and volume fractions of tissue compartments with improved robustness and accuracy. Our ℓ0 algorithm is general and can be applied to sparse estimation problems beyond the scope of this paper.

Full text links

We have located links that may give you full text access.
Can't access the paper?
Try logging in through your university/institutional subscription. For a smoother one-click institutional access experience, please use our mobile app.

For the best experience, use the Read mobile app

Mobile app image

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app

All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.

By using this service, you agree to our terms of use and privacy policy.

Your Privacy Choices Toggle icon

You can now claim free CME credits for this literature searchClaim now

Get seemless 1-tap access through your institution/university

For the best experience, use the Read mobile app