We have located links that may give you full text access.
A MYCN-MRN complex axis controls replication stress for the safe expansion of neuroprogenitor cells.
Molecular & Cellular Oncology 2016 March
DNA replication must be tightly regulated to ensure accurate duplication of the genome and its transfer to the daughter cells. When these regulatory mechanisms fail, replicative stress and DNA damage ensue, eventually leading to cell cycle inhibition or cell death. We have recently uncovered that MYCN-dependent expansion of neuroprogenitor cells is accompanied by replication stress, which is restrained by the MRN complex, a direct transcriptional target of the MYCN proto-oncogene.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app