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Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
A Cap for Every Occasion: Alternative eIF4F Complexes.
Trends in Biochemical Sciences 2016 October
The eukaryotic translation initiation factor 4F (eIF4F) has become essentially synonymous with 5' cap-dependent mRNA translation. Recent studies demonstrate that cells assemble variants of eIF4F to produce adaptive, cap-dependent translatomes during physiological conditions that inhibit eIF4F. These findings challenge us to reassess classical perceptions of cellular translational pathways.
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