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The KAT's Out of the Bag: Histone Acetylation Promotes Centromere Assembly.

Jason Palladino, Barbara G Mellone
Developmental Cell 2016 June 7
Heterochromatin is incompatible with centromeric chromatin assembly and propagation. In this issue of Developmental Cell, Ohzeki et al. (2016) reveal that a critical role of the Mis18 complex is to transiently recruit the lysine acetyltransferase KAT7 to centromeres to facilitate the removal of H3K9me3 and the deposition of CENP-A.

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