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Differences in Red Blood Cell Indices Do Not Explain Racial Disparity in Hemoglobin A1c in Children with Type 1 Diabetes.

Mahmoud Adeeb Ahmad Hamdan, James M Hempe, Cruz Velasco-Gonzalez, Ricardo Gomez, Alfonso Vargas, Stuart Chalew
Journal of Pediatrics 2016 September
We assessed the association of erythrocyte indices on mean blood glucose-independent racial disparity in hemoglobin A1c (HbA1c) in youth with type 1 diabetes. Blacks still had higher HbA1c after adjustment for mean blood glucose, red blood cell indices, age, and sex. Such differences need to be taken into account when interpreting HbA1c in Black patients.

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