MR enterography with oral contrast agent composed of methylcellulose, low-dose barium sulfate, sorbitol, and lactulose: assessment of diagnostic performance, reliability, image quality, and patient tolerance.

OBJECTIVE: The objective was to show efficiency of magnetic resonance enterography (MRE) with our previously assessed new oral contrast agent.

MATERIALS AND METHODS: Each bowel segments was evaluated for luminal distension, wall conspicuity, wall thickening, and hyperintensity on fat-saturated (FS) T2-weighted and contrast enhancement on postcontrast FS T1-weighted images. Also, consensus scoring results of MRE exams were compared with the gold standard tests in terms of active inflammatory bowel disease detection.

RESULTS: Sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of MRE for active inflammatory bowel disease detection were 62%, 98%, 80%, 96%, and 71.4%, respectively.

CONCLUSION: MRE obtained with the new mixture has a high reliability and shows good correlation with endoscopic examination±biopsy.