Non-canonical RAN Translation of CGG Repeats Has Canonical Requirements.

Diana C Cox, Thomas A Cooper

Molecular Cell 2016 April 22

Repeat expansions cause dominantly inherited neurological disorders. In this issue of Molecular Cell, Kearse et al. (2016) examine the requirements for RAN translation of the CGG repeats that cause fragile X-associated tremor/ataxia syndrome, revealing similarities and differences with canonical translation.

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