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Bad Ac-etylated Tau.

Jane C Hettinger, John R Cirrito
Neuron 2016 April 21
By using a tau construct with two mimicked acetylation sites as identified in AD brains, Tracy et al. (2016) found that acetylated tau promotes synaptic dysfunction through disruption of postsynaptic KIBRA signaling pathways, actin dynamics, and AMPA receptor trafficking.

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