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Mechanobiology in the management of mobile atrophic and oligotrophic tibial nonunions.
Journal of Orthopaedics 2015 December
BACKGROUND: Recent research indicates that atrophic nonunions are biologically active and may heal in the optimal biomechanical environment.
METHODS: Thirty-three patients with mobile atrophic and oligotrophic tibial nonunions were treated with circular external fixation and functional rehabilitation. Seven patients required autogenous bone graft procedures.
RESULTS: Bony union was achieved after the initial surgery in 31/33 (93.9%) tibias. Two persistent nonunions were successfully treated with repeat circular external fixation without bone graft. This resulted in final bony union in 33/33 (100%) patients.
CONCLUSION: Mechanobiological stimulation of tibial nonunions can produce union even if the biological activity appears to be low.
METHODS: Thirty-three patients with mobile atrophic and oligotrophic tibial nonunions were treated with circular external fixation and functional rehabilitation. Seven patients required autogenous bone graft procedures.
RESULTS: Bony union was achieved after the initial surgery in 31/33 (93.9%) tibias. Two persistent nonunions were successfully treated with repeat circular external fixation without bone graft. This resulted in final bony union in 33/33 (100%) patients.
CONCLUSION: Mechanobiological stimulation of tibial nonunions can produce union even if the biological activity appears to be low.
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