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JOURNAL ARTICLE
REVIEW
[Albinism and the Range of Fundus Hypopigmentation, Macular Hypoplasia, and Nystagmus].
Klinische Monatsblätter Für Augenheilkunde 2016 March
From the ophthalmological view, albinism is a disorder of reduced pigmentation of the retinal and irdial pigment epithelium and the iris and choroid stroma. The reduced pigmentation is accompanied by morphological changes in the retina and the optic nerve. The functional relationship of these morphological changes is not yet well understood. This review summarises the genetic causes of reduced pigment synthesis and impaired pigment distribution, and discusses the variability of expression of albinism symptoms, in the light of other disorders affecting retinal development.
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