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Research Support, Non-U.S. Gov't
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New Small Plasmid Harboring blaKPC-2 in Pseudomonas aeruginosa.

Renata Galetti, Leonardo Neves Andrade, Michael Chandler, Alessandro de Mello Varani, Ana Lúcia Costa Darini
Antimicrobial Agents and Chemotherapy 2016 May
The aim of this study was to characterize the genetic context of blaKPC-2 in Pseudomonas aeruginosa sequence type 244 from Brazil. The blaKPC-2 gene was detected in a new small plasmid, pBH6. Complete sequencing revealed that pBH6 was 3,652 bp long and included the Tn3 resolvase and Tn3 inverted repeat (IR), a partial copy of ISKpn6, and a putative ori region but no rep genes. pBH6 replicated stably into Escherichia coli strain DH10B and P. aeruginosa strain PAO.

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