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JOURNAL ARTICLE
REVIEW
Metformin: an Old Therapy that Deserves a New Indication for the Treatment of Obesity.
Current Atherosclerosis Reports 2016 April
Metformin is not currently used for weight loss or diabetes prevention because it lacks an FDA indication for obesity and/or pre-diabetes treatment. Based on the evidence, metformin has been shown to decrease the incidence of type 2 diabetes, and compares favorably to other weight-loss medications in terms of efficacy as well as safety. Thus, metformin should be considered for a treatment indication in patients with these conditions.
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