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Journal Article
Review
Circulating RNAs in medical diagnostics and as disease-relevant biomarkers.
Die Pharmazie 2016 January
The development of malignant tumors from healthy tissues is associated with profound changes in expression profiles of a large number of mRNAs, miRNAs and IncRNAs. These changes on the one hand permit insights into the biology of individual tumors; on the other hand, tumor-derived RNAs can also be detected in circulating blood and serve as specific markers for differential diagnosis and patient prognosis.
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