We have located links that may give you full text access.
Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Blinded Clinical Evaluation of a New Toothbrush Design.
OBJECTIVE: The purpose of this single-blind, crossover study was to compare plaque removal associated with a new manual toothbrush, the O'Nano and a best-selling, commercially available manual toothbrush, the Oral-B Indicator 40. The O'Nano toothbrush has a patented "one-piece molded design" made of Thermal Plastic Urethane, a plastic that has been used in medical devices.
METHODOLOGY: Over a six-week period, 40 subjects participated. Following random assignment, 22 subjects started with the O'Nano brush and the remaining started with the Oral-B Indicator 40 brush. Crossover occurred after two-weeks' use of each brush (two-week washout in between). Plaque was scored before and after brushing using the Turesky modification of the Quigley-Hein Index (T/Q-H). Plaque accumulation was 12 to 18 hours prior to examination and brushing.
RESULTS: Thirty-nine subjects completed the study; one subject was dropped for non-compliance. Groups were virtually identical at the onset in plaque level scores by study design. In comparison to baseline, both brushes achieved significant (p < 0.001) plaque reductions (gains) with a matched-paired comparison t-test. The O'Nano brush gain was 0.445 (18%) per subject and the Oral-B Indicator 40 brush was 0.504 (20%) per subject. The difference in plaque removal capability between brushes averaged 0.60 in favor of the Oral-B Indicator 40 brush, a non-significant (p = 0.20) finding determined by a matched-paired comparison t-test, which is identical to the repeated measures ANOVA when there are two groups and two time periods. Standard deviation (SD) was smaller for the O'Nano brush in plaque reduction scores (0.183 < 0.235). This difference was tested and found to be non-significant with this particular group size.
CONCLUSION: Statistical analysis of T/Q-H scores demonstrated that the O'Nano brush is comparable to the Oral-B Indicator 40 brush under the conditions of this study protocol. With this small study group the slight differences in plaque removal efficiency between both brushes was not significant. The unique "one-piece molded" design of the O'Nano brush was not evaluated for durability in comparison to a more conventional brush, the Oral-B 40.
METHODOLOGY: Over a six-week period, 40 subjects participated. Following random assignment, 22 subjects started with the O'Nano brush and the remaining started with the Oral-B Indicator 40 brush. Crossover occurred after two-weeks' use of each brush (two-week washout in between). Plaque was scored before and after brushing using the Turesky modification of the Quigley-Hein Index (T/Q-H). Plaque accumulation was 12 to 18 hours prior to examination and brushing.
RESULTS: Thirty-nine subjects completed the study; one subject was dropped for non-compliance. Groups were virtually identical at the onset in plaque level scores by study design. In comparison to baseline, both brushes achieved significant (p < 0.001) plaque reductions (gains) with a matched-paired comparison t-test. The O'Nano brush gain was 0.445 (18%) per subject and the Oral-B Indicator 40 brush was 0.504 (20%) per subject. The difference in plaque removal capability between brushes averaged 0.60 in favor of the Oral-B Indicator 40 brush, a non-significant (p = 0.20) finding determined by a matched-paired comparison t-test, which is identical to the repeated measures ANOVA when there are two groups and two time periods. Standard deviation (SD) was smaller for the O'Nano brush in plaque reduction scores (0.183 < 0.235). This difference was tested and found to be non-significant with this particular group size.
CONCLUSION: Statistical analysis of T/Q-H scores demonstrated that the O'Nano brush is comparable to the Oral-B Indicator 40 brush under the conditions of this study protocol. With this small study group the slight differences in plaque removal efficiency between both brushes was not significant. The unique "one-piece molded" design of the O'Nano brush was not evaluated for durability in comparison to a more conventional brush, the Oral-B 40.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app