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Journal Article
Research Support, N.I.H., Extramural
Review
Chromatin-remodeling and the initiation of transcription.
Quarterly Reviews of Biophysics 2015 November
The nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the SWI/SNF-RSC family of chromatin-remodeling complexes. Research reviewed here has revealed the essential features of the remodeling process.
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