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Treatment of multi-infarct dementia with citicholine.

A double-blind placebo controlled trial was conducted in 146 patients with MID who were allocated randomly into two groups, one receiving 250 mg citi-choline three times day and the other receiving isotonic saline three times a day for 2 months. The group treated with citicholine showed a marked improvement on the MMSE compared with the placebo group. No significant side effects were noted.

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