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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
REVIEW
PHACE syndrome--clinical features, aetiology and management.
Acta Paediatrica 2016 Februrary
UNLABELLED: PHACE syndrome comprises a spectrum of anomalies including posterior fossa malformations, haemangioma, arterial anomalies, cardiac defects and eye anomalies. PHACE should be considered in any patient with a large facial segmental infantile haemangioma (IH), and multidisciplinary management is crucial. Low-dose propranolol is effectively for the treatment of IH associated with PHACE syndrome. Recent evidence suggests IH is comprised of mesoderm-derived haemogenic endothelium.
CONCLUSION: The embryonic developmental anomaly nature of IH provides an insight into the origin of PHACE syndrome.
CONCLUSION: The embryonic developmental anomaly nature of IH provides an insight into the origin of PHACE syndrome.
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