Isolated Xanthoma Of The Sphenoid Sinus: A Rare Presentation.

OBJECTIVE: To present the first case in the English literature of a sphenoid xanthoma.

METHODS: Case Report

DISCUSSION: A 36 year-old Hispanic female with past medical history of Hashimoto's hypothyroidism and family history of hyperlipidemia that presented with a 1-year history of sporadic left sided epistaxis. A paranasal sinus Computed Tomography (CT) was performed revealing a soft tissue lesion infiltrating the left sphenoid sinus. Patient underwent endoscopic sinus sphenoidotomy with intraoperative findings of a yellow-tan, friable soft tissue mass filling the left sphenoid sinus. Biopsies were taken which exhibited histologically findings consistent with a xanthoma.

CONCLUSION: In a patient with hyperlipidemia isolated lesions on paransasal sinuses can be related to xanthoma formation.