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ILC Lineage Specification: To Be or Not 11b, That Is the Question.

Tomasz Kostrzewski, Hugh J M Brady
Immunity 2015 August 19
The transcription factor Bcl11b is important for T cell development and maintaining their phenotype. In this issue of Immunity, Califano et al. (2015) show that Bcl11b has a role in specifying type II innate lymphoid cell (ILC2) identity and blocks their conversion to ILC3s.

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