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Acute Liver Toxicity due to Efavirenz/Emtricitabine/Tenofovir.

Rashmee Patil, Mel A Ona, Haris Papafragkakis, Jeanne Carey, Yitzchak Moshenyat, Adib Alhaddad, Sury Anand
Case Reports in Hepatology 2015
The fixed-dose combination of Efavirenz/Emtricitabine/Tenofovir is a first-line agent for the treatment of HIV; however few cases have reported hepatotoxicity associated with the drug. We report a case of Efavirenz/Emtricitabine/Tenofovir-associated hepatotoxicity presenting mainly with hepatocellular injury characterized by extremely elevated aminotransferase levels, which resolved without acute liver failure or need for liver transplant referral.

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