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Domino aryne precursor: efficient construction of 2,4-disubstituted benzothiazoles.
Journal of the American Chemical Society 2015 May 7
An aryne precursor with a potential to perform domino aryne chemistry was proposed and synthesized. The reaction of this reagent with benzothioamide derivatives could afford 2,4-disubstituted benzothiazole with sequential incorporation of C-S, C-N, and C-C bonds on the consecutive three positions of the aryne precursor.
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