[Hyperglycemia as a risk factor of complicated acute myocardial infarction in patients of elderly and senile age].

AIM: To study clinical manifestations and functional state of myocardium in diabetic patients and in patients of elderly and senile age with myocardial infarction (MI) free of type 2 diabetes mellitus (DM) with transient hyperglycemia (HG).

MATERIALS AND METHODS: The study included 170 patients with acute macrofocal and transmural MI (with Q-wave). They were divided into group 1 comprised of diabetic patients with MI (n = 60; 36 men and 24 women; age median 78.0 (72.5-83.0 years)), group 2 with MI and TH (n = 60, 38 men, 22 women having no diabetes or disturbances of carbohydrate metabolism in the history; age median 77 (67.0-81.0 years)), and group 3 (n = 50, 28 men, 22 women with MI and normal glycemia in the acute period; age median 73.5 (66.0-83.0 years)).

RESULTS: Diabetic patients with TH more frequently than normoglycemic ones showed complicated acute Iaccompanied by acute left ventricular insufficiency, arrhythmia, and lethal outcome. Decrease of their left ventricular systolic function was more pronounced than in controls. Patients with MIIand DM and those with MI and TH had a higher frequency of mitral regurgitation. CCONCLUSION:Hvyerglycemia is significant for the evaluation clinical course and outcome of Ml.