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Journal Article
Gene-ectomy: gene ablation with CRISPR/Cas9 in human hematopoietic cells.
Cell Stem Cell 2014 November 7
CRISPR/Cas9 has recently been introduced as a gene editing tool and shows considerable promise. In this issue of Cell Stem Cell, Mandal et al. (2014) show efficient CRISPR/Cas9-mediated ablation of the CCR5 and B2M genes in primary human hematopoietic cells, two editing strategies that are potentially translatable into clinical application.
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