We have located links that may give you full text access.
[ED50 of dexmedetomidine nasal drip in induction of hypnosis in children during computed tomography].
Zhonghua Yi Xue za Zhi [Chinese medical journal] 2014 June 25
OBJECTIVE: To explore the 50% effective dose (ED₅₀) of dexmedetomidine nasal drip in the induction of hypnosis in children during computed tomography (CT).
METHODS: A total of 34 American Society of Anesthesiologists (ASA)I-IIautistic children scheduled for brain CT examination were studied. The induction was made by dexmedetomidine nasal drip and the ED₅₀ of dexmedetomidine determined by up-and down sequential experiment.When eyelash reflex became lost or Ramsay score was ≥ 4 in 1 hour after dosing, hypnosis was achieved. The study ended after 8 crossovers (successive "accept" and "refuse").
RESULTS: Among them, the ED₅₀ of dexmedetomidine was 1.76 µg/kg (95% confident interval:1.64-1.88 µg/kg).
CONCLUSION: The ED₅₀ of dexmedetomidine nasal drip is 1.76 µg/kg in the induction of hypnosis in children.
METHODS: A total of 34 American Society of Anesthesiologists (ASA)I-IIautistic children scheduled for brain CT examination were studied. The induction was made by dexmedetomidine nasal drip and the ED₅₀ of dexmedetomidine determined by up-and down sequential experiment.When eyelash reflex became lost or Ramsay score was ≥ 4 in 1 hour after dosing, hypnosis was achieved. The study ended after 8 crossovers (successive "accept" and "refuse").
RESULTS: Among them, the ED₅₀ of dexmedetomidine was 1.76 µg/kg (95% confident interval:1.64-1.88 µg/kg).
CONCLUSION: The ED₅₀ of dexmedetomidine nasal drip is 1.76 µg/kg in the induction of hypnosis in children.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices 
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app