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Ménage à trois: Sustained therapeutic anti-tumor immunity requires multiple partners in malignant glioma.
Oncoimmunology 2014
Glioblastoma is an aggressive primary brain cancer. Given our interest in novel immunotherapies, we have recently shown that inhibiting CTLA-4, PD-L1 and IDO results in a dramatic survival advantage in mice with brain tumors. Our preclinical study supports the rapid translation of this approach into phase I clinical trial.
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