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Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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Metabolism goes viral.

Shigeki J Miyake-Stoner, Clodagh C O'Shea
Cell Metabolism 2014 April 2
Viral and cellular oncogenes converge in targeting critical protein interaction networks to reprogram the cellular DNA and protein replication machinery for pathological replication. In this issue, Thai et al. (2014) show that adenovirus E4ORF1 activates MYC glycolytic targets to induce a Warburg-like effect that converts glucose into nucleotides for viral replication.

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