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CASE REPORTS
JOURNAL ARTICLE
Lemierre's syndrome with double heterozygote status in the methylenetetrahydrofolate reductase gene.
World Journal of Pediatrics : WJP 2014 August
BACKGROUND: There are some risk factors being more vulnerable to Lemierre's syndrome such as a hypercoagulable state.
METHODS: We report a rare case of Lemierre's syndrome with ethmoid and maxillary sinusitis, bilateral mastoiditis, and sigmoid sinus thrombosis.
RESULTS: Genetic study revealed a double heterozygote status in the methylenetetrahydrofolate reductase gene including C677T and A1298C.
CONCLUSION: It is suggested to screen patients with Lemierre's syndrome for a hypercoagulable state to consider anticoagulant therapy.
METHODS: We report a rare case of Lemierre's syndrome with ethmoid and maxillary sinusitis, bilateral mastoiditis, and sigmoid sinus thrombosis.
RESULTS: Genetic study revealed a double heterozygote status in the methylenetetrahydrofolate reductase gene including C677T and A1298C.
CONCLUSION: It is suggested to screen patients with Lemierre's syndrome for a hypercoagulable state to consider anticoagulant therapy.
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