Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
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Total variation-stokes strategy for sparse-view X-ray CT image reconstruction.

Previous studies have shown that by minimizing the total variation (TV) of the to-be-estimated image with some data and/or other constraints, a piecewise-smooth X-ray computed tomography image can be reconstructed from sparse-view projection data. However, due to the piecewise constant assumption for the TV model, the reconstructed images are frequently reported to suffer from the blocky or patchy artifacts. To eliminate this drawback, we present a total variation-stokes-projection onto convex sets (TVS-POCS) reconstruction method in this paper. The TVS model is derived by introducing isophote directions for the purpose of recovering possible missing information in the sparse-view data situation. Thus the desired consistencies along both the normal and the tangent directions are preserved in the resulting images. Compared to the previous TV-based image reconstruction algorithms, the preserved consistencies by the TVS-POCS method are expected to generate noticeable gains in terms of eliminating the patchy artifacts and preserving subtle structures. To evaluate the presented TVS-POCS method, both qualitative and quantitative studies were performed using digital phantom, physical phantom and clinical data experiments. The results reveal that the presented method can yield images with several noticeable gains, measured by the universal quality index and the full-width-at-half-maximum merit, as compared to its corresponding TV-based algorithms. In addition, the results further indicate that the TVS-POCS method approaches to the gold standard result of the filtered back-projection reconstruction in the full-view data case as theoretically expected, while most previous iterative methods may fail in the full-view case because of their artificial textures in the results.

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