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Synthesis and characterization of Schiff's bases of sulfamethoxazole.

BACKGROUND: Schiff's bases are excellent ligands which are synthesized from the condensation of primary amines with carbonyl groups.

FINDINGS: The classical reaction for the synthesis of Schiff's bases in an ethanolic solution and glacial acetic acid as a catalyst was followed in the synthesis of substituted sulfamethoxazole compounds.

CONCLUSIONS: Some Schiff's bases containing sulfamethoxazole nucleus have been synthesized and characterized. The present compounds are hoped to be applied in the photostability of PVC.

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