JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
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SdrA, a new DeoR family regulator involved in Streptomyces avermitilis morphological development and antibiotic production.

The SAV3339 (SdrA) protein of Streptomyces avermitilis, a member of the DeoR family of regulators, was assessed to determine its in vivo function by gene knockdown through the use of cis-encoded noncoding RNA and knockout of the sdrA gene. These analyses revealed that SdrA represents another class of Streptomyces regulator that controls morphological development and antibiotic production.

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