We have located links that may give you full text access.
ENGLISH ABSTRACT
JOURNAL ARTICLE
[Simultaneous determination of six adulterants in functional foods by high performance liquid chromatography with diode array detection].
Sichuan da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition 2013 January
OBJECTIVE: To establish a method for simultaneous determination of six adulterants including norpseudoephedrine (NPE), pseudoephedrine (PSE), amfepramone (AMF), strychnine (STR), fenfluramine (FEN) and sildenafil (SIL) in functional foods by high performance liquid chromatography with diode array detection (HPLC-DAD).
METHODS: Food samples were treated with 2% formic acid ultrasonically, and then the extracts were cleaned-up with solid phase extraction (SPE) with strong cation exchange cartridges (SCX). The sample solution was separated on a C18 column with the mobile phase composed of 0.05 mol/L potassium dihydrogen phosphate (pH3.0) and acetonitrile. The qualitative analysis was accomplished with spectral and retention times of the chromatographic peaks. The external standard curves were established for quantification of the adulterants.
RESULTS: The linear correlation coefficients of the 6 chemicals were greater than 0.999. The intraday RSDs were 6.25%-8.19% and the interday RSDs were 6.61%-10.8% with the average recoveries of 80.5%-110.0%. The detection limits of the method were 15.9-66.5 microg/kg.
CONCLUSION: The method is simple, sensitive and inexpensive and is suitable to the determination of the 6 chemicals in functional foods.
METHODS: Food samples were treated with 2% formic acid ultrasonically, and then the extracts were cleaned-up with solid phase extraction (SPE) with strong cation exchange cartridges (SCX). The sample solution was separated on a C18 column with the mobile phase composed of 0.05 mol/L potassium dihydrogen phosphate (pH3.0) and acetonitrile. The qualitative analysis was accomplished with spectral and retention times of the chromatographic peaks. The external standard curves were established for quantification of the adulterants.
RESULTS: The linear correlation coefficients of the 6 chemicals were greater than 0.999. The intraday RSDs were 6.25%-8.19% and the interday RSDs were 6.61%-10.8% with the average recoveries of 80.5%-110.0%. The detection limits of the method were 15.9-66.5 microg/kg.
CONCLUSION: The method is simple, sensitive and inexpensive and is suitable to the determination of the 6 chemicals in functional foods.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app