Correlation between central corneal thickness, anterior chamber depth, and corneal keratometry as measured by Oculyzer II and WaveLight OB820 in preoperative cataract surgery patients.

PURPOSE: To compare and correlate central corneal thickness (CCT), anterior chamber depth (ACD), and keratometric (flat and steep K) measurements using two anterior segment imaging methods, a Scheimpflug camera system (Oculyzer II [Oculus Optikgeräte GmbH]) and a partial coherence biometry system (WaveLight OB820 [Alcon Laboratories Inc]) in eyes undergoing cataract surgery.

METHODS: Ninety patients (mean age: 66±13 years [range: 32 to 88 years]) underwent preoperative measurement of CCT, ACD, and keratometric measurements by Scheimpflug tomography (Oculyzer II) and optical low coherence reflectometry (WaveLight OB820). Interdevice agreement and correlation between the two techniques were assessed.

RESULTS: All measurements were highly correlated and showed no clinically significant difference between methods. Mean CCT was 554.21±39.07 μm and 546.59±37.75 μm for the Oculyzer II and WaveLight OB820, respectively (R²=0.9268). Mean ACD was 2.63±0.44 mm and 2.63±0.43 mm for the Oculyzer II and WaveLight OB820, respectively (R(2)=0.9488). The principal meridian keratometric values were also highly correlated. Mean flat K was 42.88±1.50 diopters (D) and 42.96±1.40 D for the Oculyzer II and WaveLight OB820, respectively (R²=0.8741). Mean steep K was 44.08±1.79 D and 44.26±1.95 D for the Oculyzer II and WaveLight OB820, respectively (R(2)=0.9159).

CONCLUSIONS: Our data show that the Oculyzer II and WaveLight OB820 provide measurements that are in agreement with published values for CCT and ACD in patients. Excellent agreement for CCT and ACD was found between the two devices, as demonstrated by a high degree of correlation and linearity, in addition to minimal bias. Thus, CCT, ACD, and K measurements by these instruments can both be used in clinical preparation, and their agreement is an ensuring precision factor for cataract and refractive surgeons.