Percutaneous coronary sinus interventions to facilitate implantation of left ventricular lead: a case series and review of literature.

BACKGROUND: Valves, stenosis, and occlusion in the coronary sinus (CS) may affect the success of left ventricular (LV) lead implantation in cardiac resynchronization therapy (CRT). We present our experience in percutaneous CS intervention (PCSI) to facilitate LV lead implantation and stabilization.

METHODS AND RESULTS: Transvenous LV lead implantation was attempted for CRT in a total of 255 patients (mean age 61.0 ± 12.5 y; 60 female, 160 ischemic etiologies) from January 2005 to November 2010. Seventeen patients (6.7%) needed PCSI. PCSI indications were stenosis in 10 patients, CS valve in 5 patients, chronic venous occlusion in 1 patient, and LV lead stabilization in 1 patient. CS angioplasty was performed in 16 patients (6.2%) and stenting in 3 patients (1.2%) to facilitate LV lead placement. Two patients needed both balloon angioplasty and stenting. LV leads were successfully inserted in 15/17 (88.2%) of the patients who needed PCSI. There were no complications related to PCSI. The overall success rate of LV lead implantation increased from 238/255 (93.3%) to 253/255 (99.2%) with the use of PCSI.

CONCLUSIONS: PCSI is a useful and safe technique in transvenous LV lead placement in case of CS stenosis, valves, and lead instability.