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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
A prototype stimulator system for noninvasive Low Intensity Focused Ultrasound delivery.
A prototype Low Intensity Focused Ultrasound (LIFU) stimulator system was developed to evaluate non-invasive neuromodulation in a large animal model. We conducted a feasibility study on a Göttingen minipig, demonstrating reversible, targeted transcranial neuromodulation. The hypothalamus of the minipig was repeatedly stimulated with LIFU which evoked temporally correlated increases in both heart rate and blood pressure.
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