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Silver nanocluster aptamers: in situ generation of intrinsically fluorescent recognition ligands for protein detection.

Jaswinder Sharma, Hsin-Chih Yeh, Hyojong Yoo, James H Werner, Jennifer S Martinez
Chemical Communications : Chem Comm 2011 Februrary 29
We have synthesized an intrinsically fluorescent recognition ligand that combines the high fluorescence quantum yield (>50%) of oligonucleotide templated AgNCs with the specificity and strong binding affinity of DNA aptamers for their target proteins, to develop a new strategy for detection of specific proteins.

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