We have located links that may give you full text access.
Case Reports
Journal Article
Avascular necrosis of femoral head associated with connective tissue disease in Nigerians: case series.
West African Journal of Medicine 2009 July
BACKGROUND: Avascular Necrosis (AVN) or osteonecrosis has been frequently reported among Nigerians with sickle cell disease. Other known aetiologies include connective tissue diseases, alcohol, fat embolism, juvenile arthritis and pregnancy. Connective tissue disease (CTD) are uncommonly reported among Nigerians.
OBJECTIVE: To report the cases of three Nigerian female patients with radiological evidence of AVN associated with connective tissue diseases and inflammatory arthritis who presented to a rheumatology hospital in Lagos, Nigeria.
METHODS: The first patient was a 36-year-old woman who was initially diagnosed as systemic lupus erythematosus (SLE). After four years of treatment, she presented with intense pain in the left hip, which on radiograph showed AVN. She was initially treated with NSAIDS and narcotic analgesics. She eventually had a left hip replacement. The second patient was a 44-year-old female, who had presented seven years earlier with features of SLE. She had attended the clinic irregularly. She later developed pain in both hips and shortening of left lower limb over the preceding three years. Radiographs confirmed AVN. She was treated with analgesics. The third patient was an 18-year-old female undergraduate who had rheumatoid arthritis (RA) and later developed bilateral hip pain which on radiograph showed bilateral AVN. She was placed on analgesics and then referred for orthopaedic surgery.
CONCLUSION: Osteonecrosis may be associated with connective tissue diseases. A high index of suspicion is needed for the diagnosis, especially in SLE and RA patients with prolonged hip pain not responding to immunosuppressive.
OBJECTIVE: To report the cases of three Nigerian female patients with radiological evidence of AVN associated with connective tissue diseases and inflammatory arthritis who presented to a rheumatology hospital in Lagos, Nigeria.
METHODS: The first patient was a 36-year-old woman who was initially diagnosed as systemic lupus erythematosus (SLE). After four years of treatment, she presented with intense pain in the left hip, which on radiograph showed AVN. She was initially treated with NSAIDS and narcotic analgesics. She eventually had a left hip replacement. The second patient was a 44-year-old female, who had presented seven years earlier with features of SLE. She had attended the clinic irregularly. She later developed pain in both hips and shortening of left lower limb over the preceding three years. Radiographs confirmed AVN. She was treated with analgesics. The third patient was an 18-year-old female undergraduate who had rheumatoid arthritis (RA) and later developed bilateral hip pain which on radiograph showed bilateral AVN. She was placed on analgesics and then referred for orthopaedic surgery.
CONCLUSION: Osteonecrosis may be associated with connective tissue diseases. A high index of suspicion is needed for the diagnosis, especially in SLE and RA patients with prolonged hip pain not responding to immunosuppressive.
Full text links
Related Resources
Trending Papers
Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies.Journal of Personalized Medicine 2024 Februrary 4
Molecular Targets of Novel Therapeutics for Diabetic Kidney Disease: A New Era of Nephroprotection.International Journal of Molecular Sciences 2024 April 4
The 'Ten Commandments' for the 2023 European Society of Cardiology guidelines for the management of endocarditis.European Heart Journal 2024 April 18
A Guide to the Use of Vasopressors and Inotropes for Patients in Shock.Journal of Intensive Care Medicine 2024 April 14
Diagnosis and Management of Cardiac Sarcoidosis: A Scientific Statement From the American Heart Association.Circulation 2024 April 19
Essential thrombocythaemia: A contemporary approach with new drugs on the horizon.British Journal of Haematology 2024 April 9
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app