Clinical effectiveness of transcervical polyp resection in women with endometrial polyps: randomized controlled trial.

STUDY OBJECTIVE: To estimate the clinical effectiveness of transcervical resection of endometrial polyps.

DESIGN: Randomized controlled trial (Canadian Task Force classification I).

SETTING: University teaching hospital.

PATIENTS: One hundred fifty premenopausal women with endometrial polyps.

INTERVENTIONS: Either transcervical resection of the polyp or observation for 6 months.

MEASUREMENTS AND MAIN RESULTS: There was no difference in periodic blood loss measured using the Pictorial Blood Assessment Chart between the study groups at 6-month follow-up. A significant difference between the groups was observed in favor of the intervention group for 2 secondary outcome measures: mean difference of periodic blood loss measured using a visual analog scale (score, 0.7; 95% confidence interval, 0.11-1.30; p = .02) and occurrence of gynecologic symptoms at follow-up (7 of 75 patients [9.3%] vs 28 of 75 [37.3%]; p <.001). Data were analyzed according to the principle of intention to treat.

CONCLUSION: Transcervical resection of endometrial polyps seems to have minimal effect on periodic blood loss; however, the procedure seems to relieve symptoms such as intermenstrual bleeding in most premenopausal women.