We have located links that may give you full text access.
Comparative Study
Journal Article
Pepsinogen I concentration in organic dyspepsia patients at Gastroenterology Division, Department of Internal Medicine, Cipto Mangunkusumo Hospital.
Acta Medica Indonesiana 2009 July
AIM: To study Pepsinogen I (PG I) concentration in atrophic chronic gastritis (ACG) and non-atrophic chronic gastritis (NACG) patients with or without H. pylori infection compared to gastroscopy and biopsy as the gold standard.
METHODS: The study subjects consisted of 70 organic dyspepsia patients who underwent esofago gastroduodenoscopy (EGD) at the Gastroenterology Outpatient Clinic Department of Internal Medicine Cipto Mangunkusumo Hospital. Pepsinogen I tests were performed using ELISA with Human Pepsinogen I ELISA kit from Biohit. The data analysis used the SPSS 13 program. The ROC curve was used to find the cut off point with the best sensitivity and specificity. The proportion of positive H. Pylori was measured in percentage.
RESULTS: From the 70 organic dyspepsia patients, there were 37 subjects (52.8%) that have histopathological findings of NACG and 26 subjects (37.1%) ACG. The best cut off point for PG I concentration to predict ACG is 119 microg/L (sensitivity 70%, specificity 50%). The value of PG I concentrations between NACG and ACG patients did not differ significantly at 0.485 (p > 0.05).
CONCLUSION: The cut off point for PG I concentrations in this study did not differ significantly between NACG and ACG patients.
METHODS: The study subjects consisted of 70 organic dyspepsia patients who underwent esofago gastroduodenoscopy (EGD) at the Gastroenterology Outpatient Clinic Department of Internal Medicine Cipto Mangunkusumo Hospital. Pepsinogen I tests were performed using ELISA with Human Pepsinogen I ELISA kit from Biohit. The data analysis used the SPSS 13 program. The ROC curve was used to find the cut off point with the best sensitivity and specificity. The proportion of positive H. Pylori was measured in percentage.
RESULTS: From the 70 organic dyspepsia patients, there were 37 subjects (52.8%) that have histopathological findings of NACG and 26 subjects (37.1%) ACG. The best cut off point for PG I concentration to predict ACG is 119 microg/L (sensitivity 70%, specificity 50%). The value of PG I concentrations between NACG and ACG patients did not differ significantly at 0.485 (p > 0.05).
CONCLUSION: The cut off point for PG I concentrations in this study did not differ significantly between NACG and ACG patients.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app