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JOURNAL ARTICLE
RESEARCH SUPPORT, NON-U.S. GOV'T
[Preparation of Zhongjiefeng dispersible tablets].
OBJECTIVE: To prepare Zhongjiefeng dispersible tablets.
METHODS: The formulation of Zhongjiefeng dispersible tablets were optimized as index of disintegration time by orthogonal design test.
RESULTS: The optimized Zhongjiefeng dispersible tablets, which were prepared by selecting 16% PVPP and 3% L-HPC as disintegrants, 40% MCC as filler, can disintegrate in 3 mins.
CONCLUSIONS: The above formulation is reasonable and the disintegration time is suitable, so it can provide theoretic support for industrialization.
METHODS: The formulation of Zhongjiefeng dispersible tablets were optimized as index of disintegration time by orthogonal design test.
RESULTS: The optimized Zhongjiefeng dispersible tablets, which were prepared by selecting 16% PVPP and 3% L-HPC as disintegrants, 40% MCC as filler, can disintegrate in 3 mins.
CONCLUSIONS: The above formulation is reasonable and the disintegration time is suitable, so it can provide theoretic support for industrialization.
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