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COMPARATIVE STUDY
ENGLISH ABSTRACT
JOURNAL ARTICLE
[The use of lidocaine-coated plates (versatis) in the treatment of back pain].
Sixty patients with chronic vertebrogenic lumbalgia or lumboischialgia with exacerbation for at least 1 month were included in the study. A main group consisted of 40 patients and a control group of 20 patients. All patients took diclofenac in dosage 100 mg per day from the 1st day. Versatis was prescribed to patients of the main group from the 6th day. One-three plates were applied to the most painful spine areas and low extremities for 12 h during 5 days. To assess treatment efficacy, scales for measuring back pain, vertebral syndrome, neuropathic pain (NPS) as well as the Global Impression scale (CGI) and quality of life (EQ-5D) were used. A significant clinical effect was observed in 63% of patients of the main group: the additional reduction of pain by about a quarter, decrease of vertebral syndrome intensity, improvement of functional activity - spinal flexion-extension, ability to standing and quality of life. The NPS revealed that the use of versatis resulted in the significant decrease of "neuropathic" characteristics of pain; this effect remained after the end of treatment. The anesthetic effect of plates emerged in 1,2+/-1,1h after application, reached the maximum after 3,8+/-2,0 h, and continued during 4,7+/-2,2 h after removing the plates from the skin. The safety of lidocaine-coated plates was observed.
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