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Heterogeneity of embryonic and adult stem cells.

Thomas Graf, Matthias Stadtfeld
Cell Stem Cell 2008 November 7
New studies suggest that stem cells of embryonic, neural, and hematopoietic origin are heterogeneous, with cells moving between two or more metastable states. These cell states show a bias in their differentiation potential and correlate with specific patterns of transcription factor expression and chromatin modifications.

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