We have located links that may give you full text access.
ENGLISH ABSTRACT
JOURNAL ARTICLE
REVIEW
[Molecular aspects of the pathogenesis of inflammatory-destructive diseases of the periodontium].
Arkhiv Patologii 2006 September
The paper gives new information on the molecular mechanisms of pathogen reception in the human organism. The leading role is ascribed to the toll-like receptors recognizing the molecular structures of pathogens for bringing into operation natural resistance reactions with activation of transcription factors. Transmembrane TLRs are expressed on macrophages, dendritic, epithelial and other cells, calling for transmission of a signal of the presence of some adapter proteins. The considered effects of Porphycomonas gingivalis, the key periodontal pathogen, favor the chronic pattern of an inflammatory-destructive process due to its persistence in tissues, by inducing the expression of TLRs. It is suggested that recovered periodontal tissues in the natural structure and function are able to inhibit the expression of TLRs and to produce immune activators.
Full text links
Related Resources
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app
All material on this website is protected by copyright, Copyright © 1994-2024 by WebMD LLC.
This website also contains material copyrighted by 3rd parties.
By using this service, you agree to our terms of use and privacy policy.
Your Privacy Choices
You can now claim free CME credits for this literature searchClaim now
Get seemless 1-tap access through your institution/university
For the best experience, use the Read mobile app