[Sarcoidosis in pregnancy--diagnostic, prognostic and therapeutic problems].

INTRODUCTION: Sarcoidosis is mostfrequent in women of reproductive age, and therefore appearance of sarcoidosis in pregnant women is not rare. The diagnosis during pregnancy is difficult, and radiography should be avoided.

CASE REPORT: The aim of this work is to present a woman who presented with sarcoidosis 40 days after delivery. The patient (S.R.), was 26 years of age, a retailer and a smoker 6 pak-years. She was admitted complaining of exhaustion, fever, dispnea, chest pains and dry cought. The difficulties appeared in the second trimester of pregnancy. The patient was treated with antibiotic and symptomatic therapy for 10 days. After that she was directed in our dispensary where chest X-ray pointed to second stage of sarcoidosis. Lung function test revealed small air way obstruction. Diffusion disordes, transfer factor (Dco 59%) and diffusion coeficient reduction (DvA 62%), were registered, without reduced gas exchange. The Mx test was negative. There were no sings of extrapulmonary sarcoidosis or erytheina nodosum. The patient was treated with prednisolone. The initial dose was 40 mg per day. The dose was reduced to morbostatic dose (10 mg/day). Seven months later, all lung functions were normal later, radiographic regression was registered, and 14 months later radiographic findings were without pathological changes.

CONCLUSION: This case report confirms that sarcoidosis in pregnancy is usually associated with good prognosis.