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JOURNAL ARTICLE
REVIEW
MS-209 Schering.
Current Opinion in Investigational Drugs 2004 December
MS-209, a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. By March 2003, phase II trials in breast cancer and non-small-cell lung cancer had been initiated.
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