[Trombofilia--current status].

BACKGROUND: The trombofilia states are a special tendency to vein thrombosis that are habitually presented in young people and often they are recurrent. Their more transcendent consequences are the Lung Tromboembolismo and the Syndrome Post-trombótico.

OBJECTIVES: Keeping in mind the pathologies of the clotting that can produce trombofilia states in young patients, the prevalence of these processes was evaluated in patient with post-trombotic severe syndrome.

LOCATION: Department of Flebología and Linfología of the National Hospital of Clinical, Córdoba.

MATERIALS AND METHODS: During the period March of 2001 to March of 2002 they converged to the consultation flebológica 635 patients, of those which six of them, 3 men and 3 women smaller than 45 years, they presented severe dysfunctions of the compatible veined return with squares postromboticos. The age 39 year-old average (r: 29-45): These patients were studied by means of routine clinic, ecodoppler veined color and specific analysis of laboratory like the Resistance to the Protein activated C, Protein C, Protein S, Antibodies antifosfolipidos, Antitrombina III, Homocisteinemia.

RESULTS: Anomalous values were obtained in the biological profile of the laboratory in 3 patients; the clinical correlation and of the laboratory it was the following one: positive for protein C and Protein S; Positive for antibodies antifosfolipidos: and positive for hiperhomocisteinemia.

CONCLUSIONS: the necessary laboratory studies should be praised to discard thrombofilic states in patient smaller than 45 years that present a first thrombosis episode or any patient that has presented recurrent thrombosis. It is important to stand out that the early detection of these pathologies and the opportune derivation to the hematology, they allow to establish a preventive treatment and this way to avoid thrombotic episodes with their respective complications.