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[Experimental study on the biocompatibility and toxicology of interface between hydroxyapatite coating and bone].
According to "The standards for biological evaluation of bio-materials and bio-products abbreviated to STANDARDS" newly set by the Ministry of Health, PRC, 5 observation indexes were selected to evaluate systematically the biocompatibility and toxicology of China-made hydroxyapatite, which is clinicall used. The results revealed no effects of allergy, mutation and hemoclasis reaction except mild cytotoxicity. These indicate that the China-made hydroxyapatite meets the demand of STANDADS and thus may be clinically with safety.
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