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Incidence of pre-eclampsia in first full-term pregnancies preceded by abortion.
Journal of Obstetrics and Gynaecology 1985 October
The incidence of preeclampsia in 1st term pregnancies was studied in relation to whether or not they were preceded by pregnancies which ended in abortion--spontaneous or induced. 220 patients with previous abortion were studied along with 2 sets of controls, 1 with no previous abortion or pregnancy and 1 with a 2nd term pregnancy. The incidence of preeclampsia was significantly lower than there had been a previous induced abortion but this was not as low as in cases with a 2nd term pregnancy. This finding may be interpreted as supporting the idea that pregnancy exerts a protective effect against the risk of preeclampsia which may have an immunological basis. A mechanism is suggested to explain the apparent "protective" effect of 1st pregnancies.
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