[The use of Misoprostol preparation (Cytotec) in induction of labor at prolonged pregnancy].

OBJECTIVES: Safety and effectiveness testing of Misoprostol use at prolonged pregnancies.

DESIGN: Prospective, clinical study.

MATERIAL AND METHODS: 50 pregnant women with prolonged pregnancy, monocyesis, cephalic longitudinal foetus lie, existing foetal membranes and lack of spontaneous delivery action. Women were given 50 micrograms Misoprostol (Cytotec) to posterior vaginal fornix in case to provoke delivery. Effectiveness of inducing, delivery lasting, way of its finishing and infant condition at birth were controlled. Results were matched with control group of 35 patients with physiological pregnancy, who delivered in spontaneous partus.

RESULTS: Effective provocation was observed at 38 pregnant. Natural way delivery was observed at 40 patients. In 10 cases caesarean section was done. Lasting time of birth, way of finishing, infant condition at birth and number of complication do not differ statistically between examined and control group.

CONCLUSION: Misoprostol can be effective and save of delivery induction in prolonged pregnancy.